Catalogue

Background
The type III transforming growth factor receptor (also called betaglycan) is a cells surface heparan/chondroitin sulfate proteoglycan which binds TGF- via its core protein and is abundantly expressed in osteoblastic cells.

Synonyms: Betaglycan

Source

Immunogen: Recombinant protein derived from the extracellular domain of the chicken TGF III receptor protein. Protein shares significant homology with the mouse, rat and human sequences.

Product

Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purification Method: Ammonium Sulfate Precipitation

Concentration: See vial for concentration

Applications
Antibody can be used for Western blotting (5-10 µg/ml), immunoprecipitation (5 µg/mg of protein lysate and immunohistochemistry on paraffin embedded tissue sections (5-10 µg/ml). Optimal concentration should be evaluated by serial dilutions.

Functional Analysis: Western Blotting

Positive Control: Extraembryonic membranes from chick embryos

Storage
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Product Stability: See expiration date on vial

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References
1. Brown, C.B., et al. 'Requirement of type III TGF-β receptor for endocardial cell transformation in the heart.' Science 1999, 283, 2080-2082

Protein Reference(s)

Database Name: SwissProt

Accession Number: P16047

Species Accession: Chicken

Safety Datasheet(s) for this product: