Catalogue

Background
Orphan receptor. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Expressed predominantly in the central nervous system, and at low levels in the lung, kidney, testis, ovary and eye. Belongs to the G-protein coupled receptor 1 family.

Synonyms: Probable G Protein-Coupled Receptor GPR3

Source

Immunogen: Synthetic peptide derived from the extracellular N-terminal region of the GPR3 protein

Product

Product Form: Affinity Purified

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purification Method: Antigen Immunoaffiinity Purification

Concentration: See vial for concentration

Applications
Antibody can be used for Western blot (1-5 µg/ml). Optimal concentration should be evaluated by serial dilutions.

Functional Analysis: Western Blotting

Positive Control: Human brain

Storage
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Product Stability: See expiration date on vial

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References
1. Iismaa, T.P., et al. 'Isolation and chromosomal localization of a novel human G-protein-coupled receptor (GPR3) expressed predominantly in the central nervous system.' Genomics 1994, 24(2):391-394 2. Eggerickx, D., et al. 'Molecular cloning of an orphan G-protein-coupled receptor that constitutively activates adenylate cyclase.' Biochem. J. 1995, 309:837-843

Protein Reference(s)

Database Name: UniProt

Accession Number: P46089

Species Accession: Human

Safety Datasheet(s) for this product: