Catalogue

Background
Monocarboxylate Transporter 3 (MCT3) is a proton-linked monocarboxylate transporter. It catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate.

Synonyms: Solute carrier family 16 member 8; MCT3; SLC16A8

Source

Immunogen: Synthetic peptide derived from MCT3 protein.

Product

Product Form: Unconjugated

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide

Purification Method: Ammonium Sulfate Precipitation

Concentration: See vial for concentration

Applications
Antibody can be used for Western blotting (1-5 µg/ml starting dilution). Optimal concentration should be evaluated by serial dilutions.

Functional Analysis: Western Blotting

Positive Control: Retinal pigment epithelium

Storage
Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Product Stability: See expiration date on vial

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but our company accepts no liability for any inaccuracies or omissions in this information.

References
1. Yoon, H., et al. Cloning of the human monocarboxylate transporter MCT3 gene: localization to chromosome 22q12.3-q13.2.; Genomics 60:366-370(1999). 2. Zhu, S., et al. 'Inactivation of monocarboxylate transporter MCT3 by DNA methylation in atherosclerosis.' Circulation. 2005 Aug 30;112(9):1353-61. 3. Philip, N.J., et al. 'Loss of MCT1, MCT3, and MCT4 expression in the retinal pigment epithelium and neural retina of the 5A11/basigin-null mouse.' Invest Ophthalmol Vis Sci. 2003 Mar;44(3):1305-11.

Protein Reference(s)

Database Name: UniProt

Accession Number: O95907 (Human)

Species Accession: Human

Safety Datasheet(s) for this product: